Filmed in 1933, the movie is based on H. G. Wells' novel of the same name, published in 1897. Claude Rains stars as Dr. Jack Griffin, a chemist who discovered the secret of invisibility while conducting a series of tests involving an obscure drug called monocane.
With his face swathed in bandages and his eyes obscured by dark goggles, he takes a room at The Lion's Head Inn in an English village. He is evicted because of his behavior, and flees from the police. The drug has driven him mad, and he devises a plot to dominate the world through a reign of terror.
The film was named by the New York Times as one of the Ten Best Films of 1933, and is best known for its clever and groundbreaking visual effects. The original New York Times movie review can be read here.
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